Ibuprofen in canine endotoxin shock

The participation of prostaglandins in the physiologic alterations of endotoxin shock has been well established with the aid of prostaglandin synthetase inhibitors. Our study was designed to investigate the potential of ibuprofen, a highly specific cyclooxygenase inhibitor, to reverse the hemodynami...

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Veröffentlicht in:	The Journal of clinical investigation 1982-09, Vol.70 (3), p.536-541
Hauptverfasser:	Jacobs, E R, Soulsby, M E, Bone, R C, Wilson, Jr, F J, Hiller, F C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Pressure - drug effects Cardiac Output - drug effects Disease Models, Animal Dogs Hydrogen-Ion Concentration Ibuprofen - pharmacology Ibuprofen - therapeutic use Oxygen - blood Oxygen Consumption Shock, Septic - blood Shock, Septic - drug therapy Vascular Resistance - drug effects
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