Modeling the response of a biofilm to silver-based antimicrobial

•Preliminary efforts to integrate modeling with in vitro and in vivo studies of silver-based antimicobial.•Predicts MBC values of silver carbene complexes using aqueous solution and embedded nanoparticles.•Higher concentrations of nanoparticples are needed to reach MBC values due to slower release o...

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Veröffentlicht in:	Mathematical biosciences 2013-07, Vol.244 (1), p.29-39
Hauptverfasser:	Stine, A.E., Nassar, D., Miller, J.K., Clemons, C.B., Wilber, J.P., Young, G.W., Yun, Y.H., Cannon, C.L., Leid, J.G., Youngs, W.J., Milsted, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - pharmacology Antimicrobial Biofilm modeling Biofilms - drug effects Biofilms - growth & development Drug delivery Humans Models, Biological Nanocapsules - administration & dosage Nanoparticle Polymers - administration & dosage Silver Silver - administration & dosage Silver - pharmacology
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