Amino acid sensing in dietary-restriction-mediated longevity: roles of signal-transducing kinases GCN2 and TOR

DR (dietary restriction), or reduced food intake without malnutrition, is associated with extended longevity, improved metabolic fitness and increased stress resistance in a wide range of organisms. DR is often referred to as calorie restriction, implying that reduced energy intake is responsible fo...

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Veröffentlicht in:	Biochemical journal 2013-01, Vol.449 (1), p.1-10
Hauptverfasser:	Gallinetti, Jordan, Harputlugil, Eylul, Mitchell, James R
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - physiology Animals Caloric Restriction - methods Humans Longevity - physiology Protein Binding - physiology Protein Serine-Threonine Kinases - physiology Signal Transduction - physiology TOR Serine-Threonine Kinases - physiology
Online-Zugang:	Volltext
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