High level of susceptibility to human TRIM5α conferred by HIV-2 capsid sequences

HIV-2, which was transmitted to humans from a distant primate species (sooty mangabey), differs remarkably from HIV-1 in its infectivity, transmissibility and pathogenicity. We have tested the possibility that a greater susceptibility of HIV-2 capsid (CA) to the human restriction factor TRIM5α (hTRI...

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Veröffentlicht in:	Retrovirology 2013-05, Vol.10 (1), p.50-50, Article 50
Hauptverfasser:	Takeuchi, Junko S, Perche, Benjamin, Migraine, Julie, Mercier-Delarue, Séverine, Ponscarme, Diane, Simon, François, Clavel, François, Labrosse, Béatrice
Format:	Artikel
Sprache:	eng
Schlagworte:	Capsid Proteins - immunology Carrier Proteins - immunology HIV-2 - immunology Humans Protein Stability
Online-Zugang:	Volltext
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