The activity and copy number of mitochondrial DNA in ovine oocytes throughout oogenesis in vivo and during oocyte maturation in vitro

Mitochondria are responsible for the production of ATP, which drives cellular metabolic and biosynthetic processes. This is the first study to quantify the mtDNA copy number across all stages of oogenesis in a large monovulatory species, it includes assessment of the activity of mitochondria in germ...

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Veröffentlicht in:	Molecular human reproduction 2013-07, Vol.19 (7), p.444-450
Hauptverfasser:	Cotterill, Matthew, Harris, Sarah E, Collado Fernandez, Esther, Lu, Jianping, Huntriss, John D, Campbell, Bruce K, Picton, Helen M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals DNA, Mitochondrial - genetics Female Fluorometry Meiosis - genetics Meiosis - physiology Oocytes - metabolism Oogenesis - genetics Oogenesis - physiology Real-Time Polymerase Chain Reaction Sheep
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