Fiber Specific Changes in Sphingolipid Metabolism in Skeletal Muscles of Hyperthyroid Rats

Thyroid hormones (T 3 , T 4 ) are well known modulators of different cellular signals including the sphingomyelin pathway. However, studies regarding downstream effects of T 3 on sphingolipid metabolism in skeletal muscle are scarce. In the present work we sought to investigate the effects of hypert...

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Veröffentlicht in:	Lipids 2013-07, Vol.48 (7), p.697-704
Hauptverfasser:	Chabowski, A., Żendzian-Piotrowska, M., Mikłosz, A., Łukaszuk, B., Kurek, K., Górski, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical and Life Sciences Ceramide Ceramides - agonists Ceramides - biosynthesis Hormones Hyperthyroidism - metabolism Hyperthyroidism - pathology Injections, Subcutaneous Life Sciences Lipidology Male Medical Biochemistry Medicinal Chemistry Microbial Genetics and Genomics Muscle, Skeletal - drug effects Muscle, Skeletal - metabolism Muscles Neurochemistry Neutral Ceramidase - metabolism Nutrition Organ Specificity Original Original Article Rats Rats, Wistar Serine C-Palmitoyltransferase - metabolism Skeletal muscle Sphingolipids Sphingomyelins - agonists Sphingomyelins - biosynthesis Sphingosine - agonists Sphingosine - analogs & derivatives Sphingosine - biosynthesis Thyroid Thyroid Gland - metabolism Thyroid Gland - pathology Triiodothyronine Triiodothyronine - pharmacology
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