Alcohol-Induced Epigenetic Alterations to Developmentally Crucial Genes Regulating Neural Stemness and Differentiation

Background From studies using a diverse range of model organisms, we now acknowledge that epigenetic changes to chromatin structure provide a plausible link between environmental teratogens and alterations in gene expression leading to disease. Observations from a number of independent laboratories...

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Veröffentlicht in:	Alcoholism, clinical and experimental research clinical and experimental research, 2013-07, Vol.37 (7), p.1111-1122
Hauptverfasser:	Veazey, Kylee J., Carnahan, Mindy N., Muller, Daria, Miranda, Rajesh C., Golding, Michael C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bivalent Genes Cell Differentiation - drug effects Cell Differentiation - physiology Cells, Cultured Cerebral Cortex - cytology Cerebral Cortex - drug effects Cerebral Cortex - physiology Chromatin Epigenesis, Genetic - drug effects Epigenesis, Genetic - physiology Epigenetic Programming Ethanol - toxicity Female Fetal Alcohol Syndrome Gene Expression Regulation, Developmental Mice Mice, Inbred C57BL Neural Stem Cells Neural Stem Cells - drug effects Neural Stem Cells - physiology Pregnancy
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