Connexin 43 Channels Protect Osteocytes Against Oxidative Stress–Induced Cell Death

ABSTRACT The increased osteocyte death by oxidative stress (OS) during aging is a major cause contributing to the impairment of bone quality and bone loss. However, the underlying molecular mechanism is largely unknown. Here, we show that H2O2 induced cell death of primary osteocytes and osteocytic...

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Veröffentlicht in:Journal of bone and mineral research 2013-07, Vol.28 (7), p.1611-1621
Hauptverfasser: Kar, Rekha, Riquelme, Manuel A, Werner, Sherry, Jiang, Jean X
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Sprache:eng
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