Dynamic properties of the tight junction barrier

A principal role of tight junctions is to seal the apical intercellular space and limit paracellular flux of ions and molecules. Despite the fact that tight junctions form heavily cross‐linked structures, functional studies have fostered the hypothesis that the tight junction barrier is dynamic and...

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Veröffentlicht in:	Annals of the New York Academy of Sciences 2012-06, Vol.1257 (1), p.77-84
1. Verfasser:	Weber, Christopher R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Barriers claudin Claudins - metabolism Conductance Control Dynamic models Dynamics Epithelial Cells - metabolism Flux FRAP Humans Mathematical models Membrane Proteins - metabolism Molecular Structure occludin Occludin - metabolism Pathways Permeability tight junction Tight Junctions - chemistry Tight Junctions - metabolism ZO-1 Zonula Occludens-1 Protein - metabolism
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