Interaction of colloidal gold nanoparticles with human blood: effects on particle size and analysis of plasma protein binding profiles

Abstract Nanoparticle size and plasma binding profile contribute to a particle's longevity in the bloodstream, which can have important consequences for therapeutic efficacy. In this study an approximate doubling in nanoparticle hydrodynamic size was observed upon in vitro incubation of 30- and...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Nanomedicine 2009-06, Vol.5 (2), p.106-117
Hauptverfasser:	Dobrovolskaia, Marina A., PhD, Patri, Anil K., PhD, Zheng, Jiwen, PhD, Clogston, Jeffrey D., PhD, Ayub, Nader, Aggarwal, Parag, PhD, Neun, Barry W., BS, Hall, Jennifer B., PhD, McNeil, Scott E., PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Sites Blood Proteins - chemistry Blood Proteins - metabolism Complement Gold - chemistry Gold colloids Humans Hydrodynamic size Internal Medicine Metal Nanoparticles - chemistry Microscopy, Electron Microscopy, Scanning Probe Nanoparticles Particle Size Plasma protein binding
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!