Efflux in Acinetobacter baumannii can be determined by measuring accumulation of H33342 (bis-benzamide)

Overexpression of efflux pumps in Acinetobacter baumannii is a common mechanism of multidrug resistance in this nosocomial pathogen. Increased efflux pump expression is often assumed from MICs of antibiotics and dyes, without measurement of efflux levels. This study describes a safe, rapid and simpl...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of antimicrobial chemotherapy 2013-07, Vol.68 (7), p.1594-1600
Hauptverfasser:	Richmond, G E, Chua, K L, Piddock, L J V
Format:	Artikel
Sprache:	eng
Schlagworte:	Acinetobacter baumannii Acinetobacter baumannii - isolation & purification Acinetobacter baumannii - metabolism Acinetobacter Infections - microbiology Benzimidazoles - metabolism Bioassays Biological Transport, Active Drug resistance Fluorescent Dyes - metabolism Gene expression Gram-negative bacteria Humans Nosocomial infections Original Research Singapore Staining and Labeling - methods Strain rate
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!