Nanomaterials in the application of tumor vaccines: advantages and disadvantages

Tumor vaccines are a novel approach to the treatment of malignancy, and are attracting the attention of the medical profession. Nanomaterials have significant advantages in the preparation of a tumor vaccine, including their ability to penetrate and target cancer tissue and their antigenic propertie...

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Veröffentlicht in:OncoTargets and therapy 2013-01, Vol.6, p.629-634
Hauptverfasser: Li, Xd, Gao, Jy, Yang, Y, Fang, Hy, Han, Yj, Wang, Xm, Ge, W
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Sprache:eng
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Zusammenfassung:Tumor vaccines are a novel approach to the treatment of malignancy, and are attracting the attention of the medical profession. Nanomaterials have significant advantages in the preparation of a tumor vaccine, including their ability to penetrate and target cancer tissue and their antigenic properties. In this review, we focus on several nanomaterials, ie, carbon nanotubes, nanoemulsions, nanosized aluminum, and nanochitosan. Applications for these nanomaterials in nanovaccines and their biological characteristics, as well as their potential toxicity, are discussed.
ISSN:1178-6930
1178-6930
DOI:10.2147/OTT.S41902