Collective Activation of MRI Agents via Encapsulation and Disease-Triggered Release

An activation mechanism based on encapsulated ultrasmall gadolinium oxide nanoparticles (Gd oxide NPs) in bioresponsive polymer capsules capable of triggered release in response to chemical markers of disease (i.e., acidic pH, H2O2) is presented. Inside the hydrophobic polymeric matrices, the Gd oxi...

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Veröffentlicht in:	Journal of the American Chemical Society 2013-05, Vol.135 (21), p.7847-7850
Hauptverfasser:	Viger, Mathieu L, Sankaranarayanan, Jagadis, de Gracia Lux, Caroline, Chan, Minnie, Almutairi, Adah
Format:	Artikel
Sprache:	eng
Schlagworte:	Disease Gadolinium - administration & dosage Humans Hydrophobic and Hydrophilic Interactions Magnetic Resonance Imaging - methods Metal Nanoparticles Microscopy, Electron, Scanning Microscopy, Electron, Transmission
Online-Zugang:	Volltext
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