SNPs in genes implicated in radiation response are associated with radiotoxicity and evoke roles as predictive and prognostic biomarkers

Biomarkers are needed to individualize cancer radiation treatment. Therefore, we have investigated the association between various risk factors, including single nucleotide polymorphisms (SNPs) in candidate genes and late complications to radiotherapy in our nasopharyngeal cancer patients. A cohort...

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Veröffentlicht in:	Radiation oncology (London, England) England), 2013-05, Vol.8 (1), p.125-125
Hauptverfasser:	Alsbeih, Ghazi, El-Sebaie, Medhat, Al-Harbi, Najla, Al-Hadyan, Khaled, Shoukri, Mohamed, Al-Rajhi, Nasser
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Analysis Biological markers Biomarkers Biomarkers, Tumor - genetics Cancer Cancer therapies Carcinoma Cell cycle Chemotherapy Confidence intervals DNA repair Female Fibrosis - etiology Fibrosis - genetics Genealogy Genes Genomes Genotype Head & neck cancer Humans Male Medical research Medicine, Experimental Middle Aged Nasopharyngeal cancer Nasopharyngeal Carcinoma Nasopharyngeal Neoplasms - diagnosis Nasopharyngeal Neoplasms - genetics Nasopharyngeal Neoplasms - radiotherapy Polymorphism, Single Nucleotide Prognosis Radiation Radiation Injuries - genetics Radiation therapy Radiation Tolerance - genetics Radiotherapy - adverse effects Reverse Transcriptase Polymerase Chain Reaction Single nucleotide polymorphisms Statistical analysis Studies Thermal cycling Young Adult
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