Resveratrol Inhibits Alpha-Melanocyte-Stimulating Hormone Signaling, Viability, and Invasiveness in Melanoma Cells

Melanoma is a malignancy with high potential to invasion and treatment resistance. The α-melanocyte-stimulating hormone (α-MSH) signal transduction involving Wnt/β-catenin, c-Kit, and microphthalmia-associated transcription factor (MITF), a known pathway to produce melanin, has been demonstrated as...

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Veröffentlicht in:	Evidence-based complementary and alternative medicine 2013-01, Vol.2013 (2013), p.1-8
Hauptverfasser:	Chen, Yu-Jen, Chen, Ying-Yin, Lin, Yi-Feng, Hu, Hsuan-Yun, Liao, Hui-Fen
Format:	Artikel
Sprache:	eng
Schlagworte:	Activation Alternative medicine c-Kit protein Cancer Cancer therapies Chemotherapy Combined treatment Cytokines Dermatology Gene expression Invasiveness Kinases Leukemia Malignancy Matrix metalloproteinase Medical research Medicinal plants Melanin Melanocyte-stimulating hormone Melanoma Metalloproteinase Metastasis Microphthalmia-associated transcription factor Nuclear transport Proteins Resveratrol Signal transduction Skin cancer Stem cells Transcription factors Transduction Translocation Treatment resistance Viability Wnt protein β-Catenin
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