Enhanced Localization of Genetic Samples through Linkage-Disequilibrium Correction

Characterizing the spatial patterns of genetic diversity in human populations has a wide range of applications, from detecting genetic mutations associated with disease to inferring human history. Current approaches, including the widely used principal-component analysis, are not suited for the anal...

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Veröffentlicht in:	American journal of human genetics 2013-06, Vol.92 (6), p.882-894
Hauptverfasser:	Baran, Yael, Quintela, Inés, Carracedo, Ángel, Pasaniuc, Bogdan, Halperin, Eran
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Genetic diversity Genetic linkage Genetic Markers Genetics, Population Genome, Human Genomes Humans Linkage Disequilibrium Models, Genetic Mutation Normal distribution Phylogeography - methods Polymorphism, Single Nucleotide Principal Component Analysis Principal components analysis Software Spain
Online-Zugang:	Volltext
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