Toward the Molecular Mechanism(s) by Which EGCG Treatment Remodels Mature Amyloid Fibrils

Protein misfolding and/or aggregation has been implicated as the cause of several human diseases, such as Alzheimer’s and Parkinson’s diseases and familial amyloid polyneuropathy. These maladies are referred to as amyloid diseases, named after the cross-β-sheet amyloid fibril aggregates or deposits...

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Veröffentlicht in:	Journal of the American Chemical Society 2013-05, Vol.135 (20), p.7503-7510
Hauptverfasser:	Palhano, Fernando L, Lee, Jiyong, Grimster, Neil P, Kelly, Jeffery W
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyloid - chemistry Amyloid - metabolism Catechin - analogs & derivatives Catechin - chemical synthesis Catechin - chemistry Catechin - pharmacology HEK293 Cells Humans Models, Molecular Molecular Structure
Online-Zugang:	Volltext
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