Mechanosensitivity and compositional dynamics of cell-matrix adhesions

Cells perceive information about the biochemical and biophysical properties of their tissue microenvironment through integrin‐mediated cell–matrix adhesions, which connect the cytoskeleton with the extracellular matrix and thereby allow cohesion and long‐range mechanical connections within tissues....

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Veröffentlicht in:	EMBO reports 2013-06, Vol.14 (6), p.509-519
Hauptverfasser:	Schiller, Herbert B, Fässler, Reinhard
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesion Adhesives adhesome Animals Cell Adhesion Cell adhesion & migration Cell Adhesion Molecules - chemistry Cell Adhesion Molecules - metabolism Cellular biology Cohesion Cytoskeleton EMBO05 EMBO31 EMBO37 extracellular matrix Extracellular Matrix - physiology Feedback, Physiological focal adhesion Focal Adhesions - physiology Humans integrins Integrins - metabolism Mechanotransduction, Cellular Myosin Type II - metabolism Protein Structure, Tertiary Proteins Proteomics quantitative proteomics Review
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