Absorbable implants versus metal implants for the treatment of ankle fractures: A meta-analysis
This meta-analysis was performed to evaluate the efficiency and the safety of absorbable implants. Five major electronic databases (PubMed, Embase, Cochrane Library, SinoMed and Wanfang Data) were systematically searched for randomized controlled trials (RCTs) from their establishment to November 20...
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| Veröffentlicht in: | Experimental and therapeutic medicine 2013-05, Vol.5 (5), p.1531-1537 |
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| creator | LI, ZONG-HUAN YU, AI-XI GUO, XIAO-PENG QI, BAI-WEN ZHOU, MIN WANG, WEI-YANG |
| description | This meta-analysis was performed to evaluate the efficiency and the safety of absorbable implants. Five major electronic databases (PubMed, Embase, Cochrane Library, SinoMed and Wanfang Data) were systematically searched for randomized controlled trials (RCTs) from their establishment to November 2012. Studies on absorbable implants and metal implants for ankle fractures were selected. The meta-analysis was performed using RevMan 5.1. Ten studies with 762 patients were included and analyzed. Compared with metal implants, absorbable implants used for the internal fixation of ankle fractures produce similar radiographic and functional outcomes (P= 0.52). Normally, removal of the internal fixation is unnecessary (P |
| doi_str_mv | 10.3892/etm.2013.1017 |
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Five major electronic databases (PubMed, Embase, Cochrane Library, SinoMed and Wanfang Data) were systematically searched for randomized controlled trials (RCTs) from their establishment to November 2012. Studies on absorbable implants and metal implants for ankle fractures were selected. The meta-analysis was performed using RevMan 5.1. Ten studies with 762 patients were included and analyzed. Compared with metal implants, absorbable implants used for the internal fixation of ankle fractures produce similar radiographic and functional outcomes (P= 0.52). Normally, removal of the internal fixation is unnecessary (P<0.0001) and the incidence of palpable implants is lower (P=0.02) for absorbable implants. No statistically significant difference was observed between the two groups with regard to foreign body reactions (P=0.07), infection (P= 0.69), osteoarthritis (P= 0.39), pain (P= 0.06), refracture (P=0.67), skin necrosis (P=0.99), deep vein thrombosis (P=0.21) and nerve injury (P=0.94). Absorbable implants used in ankle fractures rarely require reoperation and result in similar functional outcomes and complications compared with metal implants. These characteristics make them efficient and reasonably safe for the treatment of ankle fractures.</description><identifier>ISSN: 1792-0981</identifier><identifier>EISSN: 1792-1015</identifier><identifier>DOI: 10.3892/etm.2013.1017</identifier><identifier>PMID: 23737914</identifier><language>eng</language><publisher>Greece: D.A. Spandidos</publisher><subject>absorbable implant ; Ankle ; ankle fracture ; Arthritis ; Biodegradation ; Clinical trials ; Fractures ; Meta-analysis ; metal implant ; Quality ; Statistical analysis ; Studies ; Surgery</subject><ispartof>Experimental and therapeutic medicine, 2013-05, Vol.5 (5), p.1531-1537</ispartof><rights>Copyright © 2013, Spandidos Publications</rights><rights>Copyright Spandidos Publications UK Ltd. 2013</rights><rights>Copyright © 2013, Spandidos Publications 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c447t-75a3c5dcfae03634729563c6715c494821813025436ad9d492da5e048393a4d63</citedby><cites>FETCH-LOGICAL-c447t-75a3c5dcfae03634729563c6715c494821813025436ad9d492da5e048393a4d63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671805/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671805/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23737914$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>LI, ZONG-HUAN</creatorcontrib><creatorcontrib>YU, AI-XI</creatorcontrib><creatorcontrib>GUO, XIAO-PENG</creatorcontrib><creatorcontrib>QI, BAI-WEN</creatorcontrib><creatorcontrib>ZHOU, MIN</creatorcontrib><creatorcontrib>WANG, WEI-YANG</creatorcontrib><title>Absorbable implants versus metal implants for the treatment of ankle fractures: A meta-analysis</title><title>Experimental and therapeutic medicine</title><addtitle>Exp Ther Med</addtitle><description>This meta-analysis was performed to evaluate the efficiency and the safety of absorbable implants. Five major electronic databases (PubMed, Embase, Cochrane Library, SinoMed and Wanfang Data) were systematically searched for randomized controlled trials (RCTs) from their establishment to November 2012. Studies on absorbable implants and metal implants for ankle fractures were selected. The meta-analysis was performed using RevMan 5.1. Ten studies with 762 patients were included and analyzed. Compared with metal implants, absorbable implants used for the internal fixation of ankle fractures produce similar radiographic and functional outcomes (P= 0.52). Normally, removal of the internal fixation is unnecessary (P<0.0001) and the incidence of palpable implants is lower (P=0.02) for absorbable implants. No statistically significant difference was observed between the two groups with regard to foreign body reactions (P=0.07), infection (P= 0.69), osteoarthritis (P= 0.39), pain (P= 0.06), refracture (P=0.67), skin necrosis (P=0.99), deep vein thrombosis (P=0.21) and nerve injury (P=0.94). Absorbable implants used in ankle fractures rarely require reoperation and result in similar functional outcomes and complications compared with metal implants. These characteristics make them efficient and reasonably safe for the treatment of ankle fractures.</description><subject>absorbable implant</subject><subject>Ankle</subject><subject>ankle fracture</subject><subject>Arthritis</subject><subject>Biodegradation</subject><subject>Clinical trials</subject><subject>Fractures</subject><subject>Meta-analysis</subject><subject>metal implant</subject><subject>Quality</subject><subject>Statistical analysis</subject><subject>Studies</subject><subject>Surgery</subject><issn>1792-0981</issn><issn>1792-1015</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNpdkd1LHDEUxUNpqWJ97GsZ8KG-zJrPSdIHYRH7AYIv9jnczWR07Mxkzc0I_vdmu-u2GgK5JL97cg-HkM-MLoSx_CzkccEpEwtGmX5HDpm2vC61er-rqTXsgBwj3tOyVMOMUR_JARdaaMvkIXHLFca0gtUQqn5cDzBlrB5DwhmrMWQY_t12MVX5LlQ5BchjmHIVuwqmP6WzS-DznAJ-q5Z_22qYYHjCHj-RDx0MGI535xH5_f3y5uJnfXX949fF8qr2UupcawXCq9Z3EKhohNTcqkb4RjPlpZWGM8ME5UqKBlrbSstbUIFKI6wA2TbiiJxvddfzagytL-MlGNw69SOkJxehd69fpv7O3cZHJ8ofhqoicLoTSPFhDpjd2KMPQ_Ee4oyOGd4orZm0BT15g97HORXDhbKCWtsYRQtVbymfImIK3X4YRt0mPVfSc5v03Ca9wn_538GefsmqAF-3AK5havs24p4pSjVVm82UYOIZ7M-iZA</recordid><startdate>20130501</startdate><enddate>20130501</enddate><creator>LI, ZONG-HUAN</creator><creator>YU, AI-XI</creator><creator>GUO, XIAO-PENG</creator><creator>QI, BAI-WEN</creator><creator>ZHOU, MIN</creator><creator>WANG, WEI-YANG</creator><general>D.A. Spandidos</general><general>Spandidos Publications UK Ltd</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20130501</creationdate><title>Absorbable implants versus metal implants for the treatment of ankle fractures: A meta-analysis</title><author>LI, ZONG-HUAN ; YU, AI-XI ; GUO, XIAO-PENG ; QI, BAI-WEN ; ZHOU, MIN ; WANG, WEI-YANG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c447t-75a3c5dcfae03634729563c6715c494821813025436ad9d492da5e048393a4d63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>absorbable implant</topic><topic>Ankle</topic><topic>ankle fracture</topic><topic>Arthritis</topic><topic>Biodegradation</topic><topic>Clinical trials</topic><topic>Fractures</topic><topic>Meta-analysis</topic><topic>metal implant</topic><topic>Quality</topic><topic>Statistical analysis</topic><topic>Studies</topic><topic>Surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>LI, ZONG-HUAN</creatorcontrib><creatorcontrib>YU, AI-XI</creatorcontrib><creatorcontrib>GUO, XIAO-PENG</creatorcontrib><creatorcontrib>QI, BAI-WEN</creatorcontrib><creatorcontrib>ZHOU, MIN</creatorcontrib><creatorcontrib>WANG, WEI-YANG</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Experimental and therapeutic medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>LI, ZONG-HUAN</au><au>YU, AI-XI</au><au>GUO, XIAO-PENG</au><au>QI, BAI-WEN</au><au>ZHOU, MIN</au><au>WANG, WEI-YANG</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Absorbable implants versus metal implants for the treatment of ankle fractures: A meta-analysis</atitle><jtitle>Experimental and therapeutic medicine</jtitle><addtitle>Exp Ther Med</addtitle><date>2013-05-01</date><risdate>2013</risdate><volume>5</volume><issue>5</issue><spage>1531</spage><epage>1537</epage><pages>1531-1537</pages><issn>1792-0981</issn><eissn>1792-1015</eissn><abstract>This meta-analysis was performed to evaluate the efficiency and the safety of absorbable implants. Five major electronic databases (PubMed, Embase, Cochrane Library, SinoMed and Wanfang Data) were systematically searched for randomized controlled trials (RCTs) from their establishment to November 2012. Studies on absorbable implants and metal implants for ankle fractures were selected. The meta-analysis was performed using RevMan 5.1. Ten studies with 762 patients were included and analyzed. Compared with metal implants, absorbable implants used for the internal fixation of ankle fractures produce similar radiographic and functional outcomes (P= 0.52). Normally, removal of the internal fixation is unnecessary (P<0.0001) and the incidence of palpable implants is lower (P=0.02) for absorbable implants. No statistically significant difference was observed between the two groups with regard to foreign body reactions (P=0.07), infection (P= 0.69), osteoarthritis (P= 0.39), pain (P= 0.06), refracture (P=0.67), skin necrosis (P=0.99), deep vein thrombosis (P=0.21) and nerve injury (P=0.94). Absorbable implants used in ankle fractures rarely require reoperation and result in similar functional outcomes and complications compared with metal implants. These characteristics make them efficient and reasonably safe for the treatment of ankle fractures.</abstract><cop>Greece</cop><pub>D.A. Spandidos</pub><pmid>23737914</pmid><doi>10.3892/etm.2013.1017</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | absorbable implant Ankle ankle fracture Arthritis Biodegradation Clinical trials Fractures Meta-analysis metal implant Quality Statistical analysis Studies Surgery |
| title | Absorbable implants versus metal implants for the treatment of ankle fractures: A meta-analysis |
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