Intracranial haemorrhage 4 days after receiving thrombolytic therapy in a young woman with myocardial infarction

Intracranial haemorrhage is a known complication after fibrinolytic therapy and occurs usually in the first 24 h. We report a 35-year-old woman who presented with severe central chest pain and she was diagnosed as anterior ST elevation myocardial infarction. She was given fibrinolytic therapy with T...

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Veröffentlicht in:BMJ case reports 2013-05, Vol.2013, p.bcr2013009816
Hauptverfasser: Ali, Sameera Mohamed, Rajani, Ali Raza, Baslaib, Fahad Omar
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Rajani, Ali Raza
Baslaib, Fahad Omar
description Intracranial haemorrhage is a known complication after fibrinolytic therapy and occurs usually in the first 24 h. We report a 35-year-old woman who presented with severe central chest pain and she was diagnosed as anterior ST elevation myocardial infarction. She was given fibrinolytic therapy with Tenecteplase. She responded well to the treatment with a decrease in the intensity of chest pain and resolution of the ST segment elevation. She was taken for coronary angiogram the next day, which revealed an occlusion of the left anterior descending (LAD) artery, and stenting of LAD was carried out. Four  days later, she developed severe headache, confusion, slurring of speech and right haemiparesis. CT brain revealed intracerebral haemorrhage and she was referred to an neurosurgeon who advised for conservative management. Her condition gradually improved with physiotherapy and was discharged home with no marked functional impairment.
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We report a 35-year-old woman who presented with severe central chest pain and she was diagnosed as anterior ST elevation myocardial infarction. She was given fibrinolytic therapy with Tenecteplase. She responded well to the treatment with a decrease in the intensity of chest pain and resolution of the ST segment elevation. She was taken for coronary angiogram the next day, which revealed an occlusion of the left anterior descending (LAD) artery, and stenting of LAD was carried out. Four  days later, she developed severe headache, confusion, slurring of speech and right haemiparesis. CT brain revealed intracerebral haemorrhage and she was referred to an neurosurgeon who advised for conservative management. 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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central
subjects Acute coronary syndromes
Adult
Cardiovascular disease
Chest Pain - diagnosis
Chest Pain - etiology
Coronary Occlusion - surgery
Coronary vessels
Diabetes
Edema
Emergency medical care
Family medical history
Female
Fibrinolytic Agents - adverse effects
Glucose
Heart attacks
Hemorrhage
Humans
Indian Sub-Continent
Intracranial Hemorrhages - chemically induced
Kinases
Middle East
Myocardial Infarction - diagnosis
Myocardial Infarction - drug therapy
Myocardial Infarction - surgery
Patients
Physical therapy
Risk factors
Tenecteplase
Thrombolytic Therapy - adverse effects
Tissue Plasminogen Activator - adverse effects
Triglycerides
Unexpected Outcome (Positive or Negative) Including Adverse Drug Reactions
Vein & artery diseases
Womens health
title Intracranial haemorrhage 4 days after receiving thrombolytic therapy in a young woman with myocardial infarction
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