Cholangiocarcinoma and brain lesions: an extremely rare finding

Cholangiocarcinoma is a rare tumour arising from either extrahepatic or intrahepatic bile ducts with an approximate occurrence of 30 640 new cases annually in the USA. 1 Common risk factors include pre-existent liver and biliary disease, parasitic diseases involving biliary tree, diabetes, obesity, HIV infection and toxic exposures. 2 Surgical resection is the mainstay of treatment for cholangiocarcinoma. 3 However, many times the disease is present at an advanced stage making surgery not amenable.