Abundance of Flt3 and its ligand in astrocytic tumors

Molecular targeted therapies for astrocytic tumors are the subject of growing research interest, due to the limited response of these tumors, especially glioblastoma multiforme, to conventional chemotherapeutic regimens. Several of these approaches exploit the inhibition of receptor tyrosine kinases...

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Veröffentlicht in:	OncoTargets and therapy 2013-01, Vol.6, p.555-561
Hauptverfasser:	Eßbach, C, Andrae, N, Pachow, D, Warnke, J-P, Wilisch-Neumann, A, Kirches, E, Mawrin, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Astrocytoma Cancer Care and treatment Cellular signal transduction fms-like tyrosine kinase-3 fms-like tyrosine kinase-3 ligand glioblastoma multiforme Kinases Ligands Mutation Oncology, Experimental Original Research Phosphotransferases Polymerase chain reaction Properties receptor tyrosine kinases Tumors
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