Markers of oxidant stress that are clinically relevant in aging and age-related disease

► A review of the current status of oxidative stress markers in aging and age-related diseases. ► This review discusses the use of different methodologies to assess oxidative stress levels. ► Particular focus on the oxidation of DNA, RNA and protein in human cohort studies with respect to aging. Des...

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Veröffentlicht in:	Mechanisms of ageing and development 2013-03, Vol.134 (3-4), p.139-157
Hauptverfasser:	Jacob, Kimberly D., Noren Hooten, Nicole, Trzeciak, Andrzej R., Evans, Michele K.
Format:	Artikel
Sprache:	eng
Schlagworte:	8-Hydroxy-2'-Deoxyguanosine Age Factors Aging Animals Biomarkers CRP Deoxyguanosine - analogs & derivatives Deoxyguanosine - pharmacology DNA Breaks, Double-Stranded DNA oxidation Erythrocytes - cytology Free Radicals Glutathione - metabolism Guanine - analogs & derivatives Guanine - pharmacology Heme - chemistry Humans Inflammation Isoprostanes - chemistry Lipid Peroxidation Oxidants - pharmacology Oxidative Stress Protein oxidation Reactive Oxygen Species RNA oxidation Single strand breaks
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