The role of genetic and autoimmune factors in premature ovarian failure

Purpose To identify the role of both genetic (number of CGG repeats in the FMR1 gene) and autoimmune factors (anti-ovarian antibodies) in premature ovarian failure (POF). Methods In cross-sectional study, 78 women with POF were divided into 3 groups by the number of CGG repeats (less than 28, 28–36,...

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Veröffentlicht in:	Journal of assisted reproduction and genetics 2013-06, Vol.30 (5), p.617-622
Hauptverfasser:	Shamilova, Nigyar N., Marchenko, Larisa A., Dolgushina, Nataliya V., Zaletaev, Dmitry V., Sukhikh, Gennady T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alleles Amenorrhea Antibodies Autoantibodies - physiology Autoimmunity - physiology Cross-Sectional Studies Disease Female Fragile X Mental Retardation Protein - genetics Gene Frequency Genetic Predisposition to Disease Gonadal Physiology and Disease Gynecology Human Genetics Humans Infertility, Female - etiology Infertility, Female - genetics Infertility, Female - immunology Infertility, Female - pathology Intellectual disabilities Laboratories Medicine Medicine & Public Health Ovaries Ovary - cytology Ovary - immunology Ovary - pathology Primary Ovarian Insufficiency - complications Primary Ovarian Insufficiency - etiology Primary Ovarian Insufficiency - genetics Primary Ovarian Insufficiency - immunology Reproductive Medicine Risk Factors Software Trinucleotide Repeats - genetics Trinucleotide Repeats - physiology Womens health X chromosomes Young Adult
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