Inositol Hexaphosphate Inhibits Tumor Growth, Vascularity, and Metabolism in TRAMP Mice: A Multiparametric Magnetic Resonance Study

Herein, employing anatomical and dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI), we evaluated noninvasively, the in vivo, chemopreventive efficacy of inositol hexaphosphate (IP6), a major constituent of high-fiber diets, against prostate tumor growth and progression in transgenic a...

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Veröffentlicht in:	Cancer prevention research (Philadelphia, Pa.) Pa.), 2013-01, Vol.6 (1), p.40-50
Hauptverfasser:	RAINA, Komal, RAVICHANDRAN, Kameswaran, RAJAMANICKAM, Subapriya, HUBER, Kendra M, SERKOVA, Natalie J, AGARWAL, Rajesh
Format:	Artikel
Sprache:	eng
Schlagworte:	AMP-Activated Protein Kinases - metabolism Animals Apoptosis Biological and medical sciences Biomarkers, Tumor - metabolism Body Weight Cell Proliferation Disease Models, Animal Disease Progression Dose-Response Relationship, Drug Glucose Transporter Type 4 - metabolism Immunohistochemistry - methods Magnetic Resonance Imaging - methods Magnetic Resonance Spectroscopy - methods Male Medical sciences Mice Mice, Inbred C57BL Mice, Transgenic Miscellaneous Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Phytic Acid - pharmacology Prevention and actions Prostatic Neoplasms - metabolism Prostatic Neoplasms - pathology Prostatic Neoplasms - prevention & control Public health. Hygiene Public health. Hygiene-occupational medicine Tumors
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