Human Mesenchymal Stem Cell Transfusion Is Safe and Improves Liver Function in Acute‐on‐Chronic Liver Failure Patients

Acute‐on‐chronic liver failure (ACLF) is a severe, life‐threatening complication, and new and efficient therapeutic strategies for liver failure are urgently needed. Mesenchymal stem cell (MSC) transfusions have been shown to reverse fulminant hepatic failure in mice and to improve liver function in...

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Veröffentlicht in:	Stem cells translational medicine 2012-10, Vol.1 (10), p.725-731
Hauptverfasser:	Shi, Ming, Zhang, Zheng, Xu, Ruonan, Lin, Hu, Fu, Junliang, Zou, Zhengsheng, Zhang, Aimin, Shi, Jianfei, Chen, Liming, Lv, Sa, He, Weiping, Geng, Hua, Jin, Lei, Liu, Zhenwen, Wang, Fu-Sheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intravenous Adult Alanine Alanine transaminase Bilirubin Bone marrow Cell Proliferation Cholinesterase Clinical trials Consent End Stage Liver Disease - therapy Female Hepatitis Hepatitis B Hepatitis B - therapy Hepatitis B - virology Hepatitis B virus - pathogenicity Hepatocytes - cytology Humans Infections Kaplan-Meier Estimate Liver Liver - metabolism Liver - pathology Liver diseases Liver failure Liver Failure, Acute - therapy Liver Function Tests Male Mesenchymal Stem Cell Transplantation - methods Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - metabolism Mesenchyme Middle Aged Mortality Prothrombin Stem cell transplantation Stem cells Studies Tissue-Specific Progenitor and Stem Cells Treatment Outcome Ultrasonic imaging Umbilical cord Umbilical Cord - cytology Viruses Young Adult
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