Resolvin D2 restores neutrophil directionality and improves survival after burns

Following severe burns and trauma injuries, the changes of neutrophil migratory phenotype are a double‐edged sword. Activated neutrophils migrate into injured tissues and help contain microbial infections, but they can also enter normal tissues and damage vital organs. Depleting the neutrophils from...

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Veröffentlicht in:	The FASEB journal 2013-06, Vol.27 (6), p.2270-2281
Hauptverfasser:	Kurihara, Tomohiro, Jones, Caroline N., Yu, Yong‐Ming, Fischman, Alan J., Watada, Susumu, Tompkins, Ronald G., Fagan, Shawn P., Irimia, Daniel
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Burns - complications Burns - drug therapy Burns - physiopathology chemotaxis Chemotaxis, Leukocyte - drug effects Chemotaxis, Leukocyte - physiology Docosahexaenoic Acids - pharmacology Docosahexaenoic Acids - physiology inflammation innate immunity lipid mediators Male microfluidics Neutrophils - drug effects Neutrophils - physiology Rats Rats, Wistar Research Communications Sepsis - complications Sepsis - drug therapy Sepsis - physiopathology
Online-Zugang:	Volltext
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