Direct visualization of cell division using high-resolution imaging of M-phase of the cell cycle

Current approaches to monitor and quantify cell division in live cells, and reliably distinguish between acytokinesis and endoreduplication, are limited and complicate determination of stem cell pool identities. Here we overcome these limitations by generating an in vivo reporter system using the sc...

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Veröffentlicht in:	Nature communications 2012-09, Vol.3 (1), p.1076-1076, Article 1076
Hauptverfasser:	Hesse, Michael, Raulf, Alexandra, Pilz, Gregor-Alexander, Haberlandt, Christian, Klein, Alexandra M., Jabs, Ronald, Zaehres, Holm, Fügemann, Christopher J., Zimmermann, Katrin, Trebicka, Jonel, Welz, Armin, Pfeifer, Alexander, Röll, Wilhelm, Kotlikoff, Michael I., Steinhäuser, Christian, Götz, Magdalena, Schöler, Hans R., Fleischmann, Bernd K.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/80/2373/2238 631/80/641/1655 Animals Brain - embryology Brain - metabolism Cell Cycle - genetics Cell Cycle - physiology Cell Division - genetics Cell Division - physiology Contractile Proteins - genetics Contractile Proteins - metabolism Embryonic Stem Cells - cytology Embryonic Stem Cells - metabolism Flow Cytometry Green Fluorescent Proteins - genetics Green Fluorescent Proteins - metabolism Heart - embryology Humanities and Social Sciences Humans In Vitro Techniques Induced Pluripotent Stem Cells - cytology Induced Pluripotent Stem Cells - metabolism Mice Mitosis - genetics Mitosis - physiology multidisciplinary Myocardial Infarction - genetics Myocardial Infarction - metabolism Science Science (multidisciplinary)
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