Effect of Irradiation on Microvascular Endothelial Cells of Parotid Glands in the Miniature Pig

Purpose To evaluate the effect of irradiation on microvascular endothelial cells in miniature pig parotid glands. Methods and Materials A single 25-Gy dose of irradiation (IR) was delivered to parotid glands of 6 miniature pigs. Three other animals served as non-IR controls. Local blood flow rate in...

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Veröffentlicht in:	International journal of radiation oncology, biology, physics biology, physics, 2010-11, Vol.78 (3), p.897-903
Hauptverfasser:	Xu, Junji, D.D.S., Ph.D, Yan, Xing, D.D.S., Ph.D, Gao, Runtao, D.D.S., Ph.D, Mao, Lisha, D.D.S, Cotrim, Ana P., D.D.S., Ph.D, Zheng, Changyu, M.D., Ph.D, Zhang, Chunmei, B.A, Baum, Bruce J., D.M.D., Ph.D, Wang, Songlin, D.D.S., Ph.D
Format:	Artikel
Sprache:	eng
Schlagworte:	ANIMAL TISSUES ANIMALS Apoptosis Aquaporin 1 - analysis Biological and medical sciences Biological effects of radiation Biomarkers - analysis Biomarkers - metabolism BLOOD FLOW BODY DOMESTIC ANIMALS Endothelial cells Endothelial Cells - radiation effects ENDOTHELIUM Fundamental and applied biological sciences. Psychology GLANDS Hematology, Oncology and Palliative Medicine In Situ Nick-End Labeling Ionizing radiations Male MAMMALS MEDICINE Microvessel density Microvessels - cytology Microvessels - radiation effects MORPHOLOGICAL CHANGES NUCLEAR MEDICINE ORGANS Parotid Gland - blood supply Parotid Gland - enzymology Parotid Gland - pathology Parotid Gland - radiation effects Platelet Endothelial Cell Adhesion Molecule-1 - analysis Radiation Dosage Radiation Injuries, Experimental - enzymology Radiation Injuries, Experimental - pathology RADIOLOGY RADIOLOGY AND NUCLEAR MEDICINE RADIOTHERAPY Regional Blood Flow - physiology Regional Blood Flow - radiation effects SALIVARY GLANDS Sphingomyelin Phosphodiesterase - analysis Sphingomyelin Phosphodiesterase - metabolism Sphingomyelinase SWINE Swine, Miniature THERAPY Tissues, organs and organisms biophysics VERTEBRATES
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