Virulent Coxiella burnetii pathotypes productively infect primary human alveolar macrophages

Summary The intracellular bacterial pathogen Coxiella burnetii is a category B select agent that causes human Q fever. In vivo, C. burnetii targets alveolar macrophages wherein the pathogen replicates in a lysosome‐like parasitophorous vacuole (PV). In vitro, C. burnetii infects a variety of culture...

Ausführliche Beschreibung