Statistical platform to discern spatial and temporal coordination of endothelial sprouting

Many biological processes, including angiogenesis, involve intercellular feedback and temporal coordination, but inference of these relations is often drowned in low sample sizes or noisy population data. To address this issue, a methodology was developed to statistically study spatial lateral inhib...

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Veröffentlicht in:	Integrative biology (Cambridge) 2012-03, Vol.4 (3), p.292-300
Hauptverfasser:	Yuen, William W, Du, Nan R, Shvartsman, Dima, Arany, Praveen R, Lam, Henry, Mooney, David J
Format:	Artikel
Sprache:	eng
Schlagworte:	angiogenesis Endothelial Cells - cytology Endothelial Cells - physiology Human Umbilical Vein Endothelial Cells Humans Ligands microscopy Models, Biological Models, Statistical Neovascularization, Physiologic - drug effects Receptors, Notch - antagonists & inhibitors Receptors, Notch - physiology Signal Transduction Systems Biology
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