Fractures after antiretroviral initiation

Bone mineral density declines by 2-6% within 1-2 years after initiation of antiretroviral therapy (ART); however, it is uncertain whether this results in an immediate or cumulative increase in fracture rates. We evaluated the incidence and predictors of fracture in 4640 HIV-positive participants fro...

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Veröffentlicht in:	AIDS (London) 2012-11, Vol.26 (17), p.2175-2184
Hauptverfasser:	YIN, Michael T, KENDALL, Michelle A, XINGYE WU, TASSIOPOULOS, Katherine, HOCHBERG, Marc, HUANG, Jeannie S, GLESBY, Marshall J, BOLIVAR, Hector, MCCOMSEY, Grace A
Format:	Artikel
Sprache:	eng
Schlagworte:	Accidental Falls - statistics & numerical data Acquired Immunodeficiency Syndrome - complications Acquired Immunodeficiency Syndrome - drug therapy Acquired Immunodeficiency Syndrome - physiopathology Adult Anti-HIV Agents - administration & dosage Anti-HIV Agents - adverse effects Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents Biological and medical sciences Body Mass Index Bone Density - drug effects CD4 Lymphocyte Count Female Follow-Up Studies Fractures, Bone - chemically induced Fractures, Bone - etiology Fractures, Bone - physiopathology Glucocorticoids - adverse effects HIV Seropositivity - complications HIV Seropositivity - drug therapy HIV Seropositivity - physiopathology Human viral diseases Humans Incidence Infectious diseases Injuries of the limb. Injuries of the spine Male Medical sciences Middle Aged Pharmacology. Drug treatments Proportional Hazards Models Retrospective Studies Smoking - adverse effects Surveys and Questionnaires Time Factors Traumas. Diseases due to physical agents Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids
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