Effect of the Use and Timing of Bone Marrow Mononuclear Cell Delivery on Left Ventricular Function After Acute Myocardial Infarction: The TIME Randomized Trial

CONTEXT While the delivery of cell therapy after ST-segment elevation myocardial infarction (STEMI) has been evaluated in previous clinical trials, the influence of the timing of cell delivery on the effect on left ventricular function has not been analyzed. OBJECTIVES To determine the effect of int...

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Veröffentlicht in:	JAMA : the journal of the American Medical Association 2012-12, Vol.308 (22), p.1-10
Hauptverfasser:	Traverse, Jay H, Henry, Timothy D, Pepine, Carl J, Willerson, James T, Zhao, David X. M, Ellis, Stephen G, Forder, John R, Anderson, R. David, Hatzopoulos, Antonis K, Penn, Marc S, Perin, Emerson C, Chambers, Jeffrey, Baran, Kenneth W, Raveendran, Ganesh, Lambert, Charles, Lerman, Amir, Simon, Daniel I, Vaughan, Douglas E, Lai, Dejian, Gee, Adrian P, Taylor, Doris A, Cogle, Christopher R, Thomas, James D, Olson, Rachel E, Bowman, Sherry, Francescon, Judy, Geither, Carrie, Handberg, Eileen, Kappenman, Casey, Westbrook, Lynette, Piller, Linda B, Simpson, Lara M, Baraniuk, Sarah, Loghin, Catalin, Aguilar, David, Richman, Sara, Zierold, Claudia, Spoon, Daniel B, Bettencourt, Judy, Sayre, Shelly L, Vojvodic, Rachel W, Skarlatos, Sonia I, Gordon, David J, Ebert, Ray F, Kwak, Minjung, Moyé, Lemuel A, Simari, Robert D
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences Bone marrow Bone Marrow Transplantation - methods Cardiology. Vascular system Coronary heart disease Delivery. Postpartum. Lactation Double-Blind Method Female General aspects Gynecology. Andrology. Obstetrics Heart Heart attacks Humans Magnetic Resonance Imaging Male Medical research Medical sciences Medical treatment Middle Aged Myocardial Infarction - complications Myocardial Infarction - therapy Time Factors Treatment Outcome Ventricular Dysfunction, Left - complications Ventricular Dysfunction, Left - therapy
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