Etv2 Is Expressed in the Yolk Sac Hematopoietic and Endothelial Progenitors and Regulates Lmo2 Gene Expression

During embryogenesis, the endothelial and the hematopoietic lineages first appear during gastrulation in the blood island of the yolk sac. We have previously reported that an Ets variant gene 2 (Etv2/ER71) mutant embryo lacks hematopoietic and endothelial lineages; however, the precise roles of Etv2...

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Veröffentlicht in:	Stem cells (Dayton, Ohio) Ohio), 2012-08, Vol.30 (8), p.1611-1623
Hauptverfasser:	Koyano-Nakagawa, Naoko, Kweon, Junghun, Iacovino, Michelina, Shi, Xiaozhong, Rasmussen, Tara L., Borges, Luciene, Zirbes, Katie M., Li, Tongbin, Perlingeiro, Rita C. R., Kyba, Michael, Garry, Daniel J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - genetics Adaptor Proteins, Signal Transducing - metabolism Animals Cell Differentiation - physiology Digestive system Disease Models, Animal Endothelial Cells - cytology Endothelial Cells - metabolism Endothelial Cells - physiology Endothelial development Etv2 Etv2 knockout Fish Gene Expression Hematopoiesis Hematopoietic Stem Cells - cytology Hematopoietic Stem Cells - metabolism Hematopoietic Stem Cells - physiology Humans Immunohistochemistry LIM Domain Proteins - genetics LIM Domain Proteins - metabolism Mice Mice, Knockout Mice, Transgenic Transcription Factors - genetics Transcription Factors - metabolism Transfection Transgenesis Yolk Sac - cytology Yolk Sac - metabolism Zebrafish
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