juxtaparanodal proteins CNTNAP2 and TAG1 regulate diet-induced obesity

Despite considerable effort, the identification of genes that regulate complex multigenic traits such as obesity has proven difficult with conventional methodologies. The use of a chromosome substitution strain-based mapping strategy based on deep congenic analysis overcame many of the difficulties...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Mammalian genome 2012-08, Vol.23 (7-8), p.431-442
Hauptverfasser:	Buchner, David A, Geisinger, Jon M, Glazebrook, Patricia A, Morgan, Michael G, Spiezio, Sabrina H, Kaiyala, Karl J, Schwartz, Michael W, Sakurai, Takeshi, Furley, Andrew J, Kunze, Diana L, Croniger, Colleen M, Nadeau, Joseph H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adiposity Adiposity - genetics adverse effects Alleles Amino Acid Sequence Amino Acid Substitution Animal Genetics and Genomics Animals Autism Biomedical and Life Sciences Body Weight Body weight gain Cell Biology chromosome substitution Chromosomes Chromosomes, Mammalian Contactin 2 Contactin 2 - deficiency Contactin 2 - genetics Contactin 2 - physiology deficiency Diet, High-Fat Diet, High-Fat - adverse effects Disease Resistance Disease Resistance - genetics Energy Intake Energy Intake - genetics Energy Metabolism Epilepsy Epistasis, Genetic etiology Feeding Female Food intake Gene mapping genes Genetic Association Studies genetic background genetics Genotype high fat diet Human Genetics Kv1.1 Potassium Channel Kv1.1 Potassium Channel - metabolism Life Sciences Male Membrane Proteins Membrane Proteins - genetics Membrane Proteins - metabolism Membrane Proteins - physiology metabolism Mice Mice, 129 Strain Mice, Congenic Mice, Inbred C57BL Mice, Knockout Molecular Sequence Data Mutation Nerve Tissue Proteins Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism Nerve Tissue Proteins - physiology Neurological diseases Obesity Obesity - etiology Obesity - genetics Obesity - metabolism Peptide mapping physiology Protein Transport proteins weight gain
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!