Phosphatidylinositol (3,4,5)-Trisphosphate Activity Probes for the Labeling and Proteomic Characterization of Protein Binding Partners

Phosphatidylinositol polyphosphate lipids, such as phosphatidylinositol (3,4,5)-trisphosphate (PI(3,4,5)P 3 ), regulate critical biological processes, many of which are aberrant in disease. These lipids often act as site-specific ligands in interactions that enforce membrane-association of protein b...

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Veröffentlicht in:	Biochemistry (Easton) 2011-11, Vol.50 (51), p.11143-11161
Hauptverfasser:	Rowland, Meng M., Bostic, Heidi E., Gong, Denghuang, Speers, Anna E., Lucas, Nathan, Cho, Wonhwa, Cravatt, Benjamin F., Best, Michael D.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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