Molecular targeted therapies in non-GIST soft tissue sarcomas: what the radiologist needs to know

Non-gastrointestinal stromal soft tissue sarcomas are uncommon neoplasms that have a dismal prognosis due to a high incidence of metastases and a poor response to conventional chemotherapy. The identification of characteristic genetic alterations in several of these tumors has opened the window for...

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Veröffentlicht in:	Cancer imaging 2013-05, Vol.13 (2), p.197-211
Hauptverfasser:	Tirumani, Sree Harsha, Jagannathan, Jyothi P, O'Regan, Kevin, Kim, Kyung Won, Shinagare, Atul B, Krajewski, Katherine M, Ramaiya, Nikhil H
Format:	Artikel
Sprache:	eng
Schlagworte:	Benzamides - therapeutic use Female Humans Imatinib Mesylate Male Piperazines - therapeutic use Protein Kinase Inhibitors - therapeutic use Pyrimidines - therapeutic use Radiography Review Sarcoma - diagnostic imaging Sarcoma - drug therapy TOR Serine-Threonine Kinases - antagonists & inhibitors
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