Conservation of functional domain structure in bicarbonate-regulated "soluble" adenylyl cyclases in bacteria and eukaryotes

Soluble adenylyl cyclase (sAC) is an evolutionarily conserved bicarbonate sensor. In mammals, it is responsible for bicarbonate-induced, cAMP-dependent processes in sperm required for fertilization and postulated to be involved in other bicarbonate- and carbon dioxide-dependent functions throughout...

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Veröffentlicht in:	Development genes and evolution 2004-10, Vol.214 (10), p.503-509
Hauptverfasser:	Kobayashi, Mime, Buck, Jochen, Levin, Lonny R
Format:	Artikel
Sprache:	eng
Schlagworte:	Actinobacteria Adenylyl Cyclases - chemistry Adenylyl Cyclases - genetics Adenylyl Cyclases - metabolism Amino Acid Sequence Animals Arthropoda Bacteria - enzymology Bacteria - genetics Bicarbonates - metabolism Chloroflexus Chloroflexus aurantiacus Chordata Cloning, Molecular Computational Biology Conservation Cyanobacteria Databases, Genetic Dictyostelium Dictyostelium - metabolism DNA Primers Eubacterium Eukaryotic Cells - enzymology Gene Expression Humans Mammals - metabolism Metazoa Molecular Sequence Data Phylogeny Plasmids - genetics Protein Structure, Tertiary Proteins Proteobacteria Sequence Alignment Sequence Analysis, DNA Species Specificity
Online-Zugang:	Volltext
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