Early Prediction of Outcome in Advanced Head-and-Neck Cancer Based on Tumor Blood Volume Alterations During Therapy: A Prospective Study

Purpose To assess whether alterations in tumor blood volume (BV) and blood flow (BF) during the early course of chemo-radiotherapy (chemo-RT) for head-and-neck cancer (HNC) predict treatment outcome. Methods and Materials Fourteen patients receiving concomitant chemo-RT for nonresectable, locally ad...

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Veröffentlicht in:	International journal of radiation oncology, biology, physics biology, physics, 2008-12, Vol.72 (5), p.1287-1290
Hauptverfasser:	Cao, Yue, Ph.D, Popovtzer, Aron, M.D, Li, Diana, B.S.E, Chepeha, Douglas B., M.D, Moyer, Jeffrey S., M.D, Prince, Mark E., M.D, Worden, Francis, M.D, Teknos, Theodoros, M.D, Bradford, Carol, M.D, Mukherji, Suresh K., M.D, Eisbruch, Avraham, M.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged, 80 and over Antibodies, Monoclonal - administration & dosage Antibodies, Monoclonal, Humanized Antineoplastic Combined Chemotherapy Protocols - therapeutic use BLOOD BLOOD FLOW Blood Volume - radiation effects Carboplatin - administration & dosage CARCINOMAS Cetuximab Combined Modality Therapy FAILURES Female Follow-Up Studies HEAD Head and neck cancer Head and Neck Neoplasms - blood supply Head and Neck Neoplasms - drug therapy Head and Neck Neoplasms - mortality Head and Neck Neoplasms - pathology Head and Neck Neoplasms - radiotherapy Hematology, Oncology and Palliative Medicine Humans Imaging Male Middle Aged NECK NMR IMAGING Paclitaxel - administration & dosage Paclitaxel - therapeutic use PATIENTS Perfusion Predictive Value of Tests Radiology RADIOLOGY AND NUCLEAR MEDICINE RADIOTHERAPY Radiotherapy Dosage Time Factors Treatment Failure Treatment Outcome
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