TH17 Cells Mediate Steroid-Resistant Airway Inflammation and Airway Hyperresponsiveness in Mice1

Steroid-resistant asthma comprises an important source of morbidity in patient populations. T H 17 cells represent a distinct population of CD4 + Th cells that mediate neutrophilic inflammation and are characterized by the production of IL-17, IL-22, and IL-6. To investigate the function of T H 17 c...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The Journal of immunology (1950) 2008-09, Vol.181 (6), p.4089-4097
Hauptverfasser:	McKinley, Laura, Alcorn, John F., Peterson, Alanna, DuPont, Rachel B., Kapadia, Shernaaz, Logar, Alison, Henry, Adam, Irvin, Charles G., Piganelli, Jon D., Ray, Anuradha, Kolls, Jay K.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!