Clawing back: broadening the notion of metal chelators in medicine

[Display omitted] ► Not all chelators are the same: more than metal sequestration and elimination. ► Metal chelates can redistribute metals across biological membranes. ► Metal-chelating fragments provide leads for metalloenzyme inhibition. ► Metal chelation can enhance metal reactivity and thus cyt...

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Veröffentlicht in:	Current opinion in chemical biology 2013-04, Vol.17 (2), p.143-149
1. Verfasser:	Franz, Katherine J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chelating Agents - chemistry Chelating Agents - pharmacology Chelating Agents - therapeutic use Chelation Therapy - methods Humans Metalloproteins - antagonists & inhibitors Metalloproteins - metabolism Tissue Distribution
Online-Zugang:	Volltext
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