Serum free light chain ratio as a biomarker for high-risk smoldering multiple myeloma

A markedly elevated serum free light chain (FLC) ratio may serve as a biomarker for malignant transformation in high-risk smoldering multiple myeloma (SMM) and identify patients who are at imminent risk of progression. We retrospectively studied the predictive value of the serum (FLC) assay in 586 p...

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Veröffentlicht in:	Leukemia 2013-04, Vol.27 (4), p.941-946
Hauptverfasser:	Larsen, J T, Kumar, S K, Dispenzieri, A, Kyle, R A, Katzmann, J A, Rajkumar, S V
Format:	Artikel
Sprache:	eng
Schlagworte:	692/699/67/1857 692/699/67/1990/804 692/700/1750 Amyloidosis Anemia Asymptomatic Biological markers Biomarkers Biomarkers, Tumor - blood Cancer Research Care and treatment Chains Critical Care Medicine Diagnosis Female Hematology Humans Hypercalcemia Immunoglobulin Light Chains - blood Intensive Internal Medicine Leukemia Light Male Medical prognosis Medical records Medicine Medicine & Public Health Middle Aged Multiple myeloma Multiple Myeloma - blood Multiple Myeloma - diagnosis Oncology original-article Patients Physiological aspects Plasma Proteins Risk ROC Curve Sensitivity and Specificity Smoldering Subgroups Working groups
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