A red/far-red light-responsive bi-stable toggle switch to control gene expression in mammalian cells

Growth and differentiation of multicellular systems is orchestrated by spatially restricted gene expression programs in specialized subpopulations. The targeted manipulation of such processes by synthetic tools with high-spatiotemporal resolution could, therefore, enable a deepened understanding of...

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Veröffentlicht in:	Nucleic acids research 2013-04, Vol.41 (7), p.e77-e77
Hauptverfasser:	Müller, Konrad, Engesser, Raphael, Metzger, Stéphanie, Schulz, Simon, Kämpf, Michael M, Busacker, Moritz, Steinberg, Thorsten, Tomakidi, Pascal, Ehrbar, Martin, Nagy, Ferenc, Timmer, Jens, Zubriggen, Matias D, Weber, Wilfried
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arabidopsis Proteins - genetics Arabidopsis Proteins - metabolism Basic Helix-Loop-Helix Transcription Factors - genetics Basic Helix-Loop-Helix Transcription Factors - metabolism Cells, Cultured Chick Embryo Cricetinae Gene Expression Regulation - radiation effects Humans Light Methods Online Mice Neovascularization, Physiologic - genetics Neovascularization, Physiologic - radiation effects Phytochrome B - genetics Phytochrome B - metabolism Transgenes
Online-Zugang:	Volltext
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