Three-dimensional hMSC Motility within Peptide-Functionalized PEG-Based Hydrogel of Varying Adhesivity and Crosslinking Density

Human mesenchymal stem cell (hMSC) migration and recruitment play a critical role during bone fracture healing. Within the complex 3D in vivo microenvironment, hMSC migration is regulated through a myriad of extracellular cues. Here, we use a thiol-ene photopolymerized hydrogel to recapitulate struc...

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Veröffentlicht in:Acta biomaterialia 2013-02, Vol.9 (5), p.6381-6392
Hauptverfasser: Kyburz, Kyle A, Anseth, Kristi S
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
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