Mechanism of cadmium induced crystal defects in developing rat tooth enamel

It is well known that exposure to environmental cadmium causes itai-itai (ouch-ouch) disease. However, the exact mechanism underlying this bone disease remains unresolved. By focusing on the calcification mechanism, we examined developing tooth enamel in rats exposed to cadmium to test the hypothesi...

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Veröffentlicht in:	Proceedings of the Japan Academy, Series B Series B, 2009, Vol.85(10), pp.500-507
Hauptverfasser:	KAKEI, Mitsuo, SAKAE, Toshiro, YOSHIKAWA, Masayoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cadmium - toxicity cadmium binding carbonic anhydrase cadmium ions Carbonic Anhydrases - metabolism crystal defects Crystallization Dental Enamel - embryology Dental Enamel - enzymology Dental Enamel - pathology Dental Enamel - ultrastructure Dental Enamel Proteins - metabolism Electrophoresis, Polyacrylamide Gel Immunoblotting itai-itai (ouch-ouch) disease Male osteoporosis Rats Rats, Sprague-Dawley Tooth - embryology Tooth - enzymology Tooth - pathology Tooth - ultrastructure tooth enamel
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