Acetylated Histone H3K9 is associated with meiotic recombination hotspots, and plays a role in recombination redundantly with other factors including the H3K4 methylase Set1 in fission yeast

Histone modifications are associated with meiotic recombination hotspots, discrete sites with augmented recombination frequency. For example, trimethylation of histone H3 lysine4 (H3K4me3) marks most hotspots in budding yeast and mouse. Modified histones are known to regulate meiotic recombination p...

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Veröffentlicht in:	Nucleic acids research 2013-04, Vol.41 (6), p.3504-3517
Hauptverfasser:	Yamada, Shintaro, Ohta, Kunihiro, Yamada, Takatomi
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Chromatin - metabolism DNA Breaks, Double-Stranded Gene Deletion Gene Regulation, Chromatin and Epigenetics Genome, Fungal Histone-Lysine N-Methyltransferase - genetics Histone-Lysine N-Methyltransferase - physiology Histones - genetics Histones - metabolism Meiosis - genetics Mutation Promoter Regions, Genetic Recombination, Genetic Schizosaccharomyces - enzymology Schizosaccharomyces - genetics Schizosaccharomyces pombe Proteins - genetics Schizosaccharomyces pombe Proteins - metabolism Schizosaccharomyces pombe Proteins - physiology Transcription Factors - genetics Transcription Factors - physiology
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