XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells

Autophagy is activated to maintain cellular energy homeostasis in response to nutrient starvation. However, au- tophagy is not persistently activated, which is poorly understood at a mechanistic level. Here, we report that turn- over of FoxO1 is involved in the dynamic autophagic process caused by g...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cell research 2013-04, Vol.23 (4), p.491-507
Hauptverfasser: Zhao, Ying, Li, Xue, Cai, Mu-Yan, Ma, Ke, Yang, Jing, Zhou, Jingyi, Fu, Wan, Wei, Fu-Zheng, Wang, Lina, Xie, Dan, Zhu, Wei-Guo
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!