XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells
Autophagy is activated to maintain cellular energy homeostasis in response to nutrient starvation. However, au- tophagy is not persistently activated, which is poorly understood at a mechanistic level. Here, we report that turn- over of FoxO1 is involved in the dynamic autophagic process caused by g...
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Veröffentlicht in: | Cell research 2013-04, Vol.23 (4), p.491-507 |
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Hauptverfasser: | , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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