Hypoglycemic effect of Brassica juncea(seeds)on streptozotocin induced diabetic male albino rat
Objective:To evaluate the hypoglycemic effect of Brassica juncea(seeds) on streptozotocin induced diabetic male albino rats.Methods:Hypoglycemic activity of Brassica juncea(seeds)aqueous extract at a dose of 250,350 and 450 mg/kg body weight was evaluated.Adult male Swiss albino rats of six numbers...
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| Veröffentlicht in: | Asian Pacific journal of tropical biomedicine 2011-08, Vol.1 (4), p.323-325 |
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| creator | Thirumalai, T Therasa, S Viviyan Elumalai, EK David, E |
| description | Objective:To evaluate the hypoglycemic effect of Brassica juncea(seeds) on streptozotocin induced diabetic male albino rats.Methods:Hypoglycemic activity of Brassica juncea(seeds)aqueous extract at a dose of 250,350 and 450 mg/kg body weight was evaluated.Adult male Swiss albino rats of six numbers in each group was undertaken for study and evaluated.Results:The serum insulin levels were recorded a significant depletion in all groups,short term as well as long term diabetic animals,when compared to that of normal animals.A significant dosage dependent augmenting effect of the seed extract on the serum insulin was recorded in both short term as well as long term groups.Conclusions:The aqueous seed extract of Brassica juncea has potent hypoglycemic activity in male albino rat. |
| doi_str_mv | 10.1016/S2221-1691(11)60052-X |
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Therasa, S Viviyan ; Elumalai, EK ; David, E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4475-30997c5e8df4b3ceac0d7c9aaf081e4773ed4f3a74a5bb57cc0188c13fd03f2f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Animals</topic><topic>Anti-diabetic</topic><topic>Ayurveda</topic><topic>Body Weight</topic><topic>Diabetes</topic><topic>Diabetes mellitus</topic><topic>Diabetes Mellitus, Experimental - drug therapy</topic><topic>Glucose Tolerance Test</topic><topic>Hypoglycemic</topic><topic>Hypoglycemic Agents - isolation & purification</topic><topic>Hypoglycemic Agents - therapeutic use</topic><topic>Insulin</topic><topic>Insulin - blood</topic><topic>Male</topic><topic>mellitus</topic><topic>Mustard Plant - chemistry</topic><topic>Original</topic><topic>Plant Extracts - isolation & purification</topic><topic>Plant Extracts - therapeutic use</topic><topic>Rats, Wistar</topic><topic>Seeds - chemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Thirumalai, T</creatorcontrib><creatorcontrib>Therasa, S Viviyan</creatorcontrib><creatorcontrib>Elumalai, EK</creatorcontrib><creatorcontrib>David, E</creatorcontrib><collection>中文科技期刊数据库</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>中文科技期刊数据库-7.0平台</collection><collection>中文科技期刊数据库-医药卫生</collection><collection>中文科技期刊数据库- 镜像站点</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Asian Pacific journal of tropical biomedicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Thirumalai, T</au><au>Therasa, S Viviyan</au><au>Elumalai, EK</au><au>David, E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hypoglycemic effect of Brassica juncea(seeds)on streptozotocin induced diabetic male albino rat</atitle><jtitle>Asian Pacific journal of tropical biomedicine</jtitle><addtitle>Asian Pacific Journal of Tropical Biomedicine</addtitle><date>2011-08-01</date><risdate>2011</risdate><volume>1</volume><issue>4</issue><spage>323</spage><epage>325</epage><pages>323-325</pages><issn>2221-1691</issn><eissn>2588-9222</eissn><abstract>Objective:To evaluate the hypoglycemic effect of Brassica juncea(seeds) on streptozotocin induced diabetic male albino rats.Methods:Hypoglycemic activity of Brassica juncea(seeds)aqueous extract at a dose of 250,350 and 450 mg/kg body weight was evaluated.Adult male Swiss albino rats of six numbers in each group was undertaken for study and evaluated.Results:The serum insulin levels were recorded a significant depletion in all groups,short term as well as long term diabetic animals,when compared to that of normal animals.A significant dosage dependent augmenting effect of the seed extract on the serum insulin was recorded in both short term as well as long term groups.Conclusions:The aqueous seed extract of Brassica juncea has potent hypoglycemic activity in male albino rat.</abstract><cop>China</cop><pub>Elsevier B.V</pub><pmid>23569784</pmid><doi>10.1016/S2221-1691(11)60052-X</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Animals Anti-diabetic Ayurveda Body Weight Diabetes Diabetes mellitus Diabetes Mellitus, Experimental - drug therapy Glucose Tolerance Test Hypoglycemic Hypoglycemic Agents - isolation & purification Hypoglycemic Agents - therapeutic use Insulin Insulin - blood Male mellitus Mustard Plant - chemistry Original Plant Extracts - isolation & purification Plant Extracts - therapeutic use Rats, Wistar Seeds - chemistry |
| title | Hypoglycemic effect of Brassica juncea(seeds)on streptozotocin induced diabetic male albino rat |
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