An LC-MS/MS Assay for Detection and Quantification of the Dipeptide Gly-Gln in Rat Brain

The enzymatic cleavage products of β-endorphin (β-endorphin 1-27 and Gly-Gln) reduce voluntary alcohol consumption in alcohol preferring P rats. Gly-Gln also inhibits the reward benefiting effects of morphine and nicotine. It would be useful for the investigation of this effect to have an analytical...

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Veröffentlicht in:	Analytical biochemistry 2012-06, Vol.425 (2), p.145-150
Hauptverfasser:	Bobba, Sudheer, Resch, Garth E., Gutheila, William G.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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