Recent Insights into the Cell Biology of Thyroid Angiofollicular Units

In thyrocytes, cell polarity is of crucial importance for proper thyroid function. Many intrinsic mechanisms of self-regulation control how the key players involved in thyroid hormone (TH) biosynthesis interact in apical microvilli, so that hazardous biochemical processes may occur without detriment...

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Veröffentlicht in:	Endocrine reviews 2013-04, Vol.34 (2), p.209-238
Hauptverfasser:	Colin, Ides M, Denef, Jean-François, Lengelé, Benoit, Many, Marie-Christine, Gérard, Anne-Catherine
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Biosynthesis Capillaries Cytoplasm Globules Goiter, Nodular - etiology Goiter, Nodular - metabolism Growth factors Humans Hypoxia Hypoxia-inducible factors Iodides Iodine Iodine - metabolism Microvasculature Morphology Neovascularization, Physiologic - physiology Nodules Nutrients Oxygen Reactive oxygen species Reviews Thyrocytes Thyroglobulin Thyroid Thyroid gland Thyroid Gland - blood supply Thyroid Gland - cytology Thyroid Gland - metabolism Thyroid Gland - physiology Thyroid Hormones - biosynthesis Thyroid Hormones - metabolism Thyroid-stimulating hormone Vascular endothelial growth factor
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